Allele frequency of known aging-associated genes

Variant ID Gene(s) Longevity

Allele(s)

 Wellderly

Population(%) #

African

(AFR)(%) $

 American

(AMR)(%) $

East Asian

(EAS)(%) $

European

(EUR)(%) $

South Asian

(SAS)(%) $

 Healthy Aging Indians(%)

*Ongoing study

rs2802292

FOXO3A

G/T

41

83

39

31

43

56

40

rs1935949

FOXO3A

A/G

31

92

34

29

35

49

48

rs5882

CETP

G/A/C

33

47

40

44

33

45

49

rs1042522

TP53

G/C/T

74

25

54

52

61

44

58

rs1800795

IL6

C/G

40

2

18

0

42

14

15

rs3803304

AKT1

C/G

73

83

71

90

73

68

33

rs9536314

KL

T/A/G

NA

20

8

NA

19

14

13

# Erikson GA et al. Cell. 2016;165:1002–11.

$ 1000 Genome Project